PEDIATRICIANS
Documented Susceptibility to Levofloxacin1
T.R.U.S.T. (Tracking Resistance in the United States Today) is the largest longitudinal surveillance program. T.R.U.S.T. annually surveys susceptibility of clinically significant pathogens during the winter respiratory season. The T.R.U.S.T. data include antimicrobial susceptibilities for some of the most common ocular pathogens, including Streptococcus pneumoniae and Haemophilus influenzae, based on respiratory, ocular, and other isolates.
Despite Wide Systemic Use, Key Pathogens Remain Susceptible
- ≥ 99% susceptibility of S pneumoniae and H influenzae in a LANDMARK, 9-year surveillance study involving over 71,000 isolates from over 200 centers, and counting
*A correlation between the in vitro systemic breakpoint and ophthalmological efficacy has not been established.
1. Data on file, VISTAKON® Pharmaceuticals. Antimicrobial susceptibility: nationwide patterns in the T.R.U.S.T. surveillance program.
Antimicrobial Susceptibility of S pneumoniae and H influenzae Ocular Isolates
- Resistance to levofloxacin due to spontaneous mutation in vitro is a rare occurrence (10-9 to 10-10)
1. Data on file, VISTAKON® Pharmaceuticals. Antimicrobial susceptibility: nationwide patterns in the T.R.U.S.T. surveillance program.
