Dual Mechanism of Action, Similar to Gatifloxacin and Moxifloxacin, Delivers Bactericidal Activity1

  • Eradicates targeted pathogens by inhibiting both topoisomerase IV and DNA gyrase enzymes
  • Interferes with DNA replication, transcription, repair, and recombination

Resistance

  • Due to spontaneous mutation resistance in vitro is a rare occurrence (10-9 to 10-10)

1. Report from the Hawaiian Eye 2007 workshop. Ocular TRUST: A new tool for ophthalmology. Ophthalmol Times. 2007;(suppl July 1):1-4.